"In our experiment, we hypothesized that obesity, type I diabetes and similar health issues were correlated with depleted levels of Akkermansia Muciniphila in the gut microbiome. In our experiments, we found that mice who were genetically predisposed to obesity had A. Muciniphila levels between 6 and 8, (log base 10) whereas lean mice had levels around 11, (figure A) which confirmed our hypothesis that A. Muciniphila levels are correlated with obesity. We tested then to see how prebiotic oligosaccharides would affect the levels of A. Muciniphila in mice. We found that in obese mice, prebiotic oligosaccharides supplemented to a control diet increased A. Muciniphila levels slightly from about 9 in control diet alone to about 10. When prebiotic oligosaccharides were supplemented with a high-fat diet, A. Muciniphila levels increased dramatically from around 7 in high-fat diet alone to about 10.5. (Figure B) Furthermore, we found that levels of lipopolysaccharides in the blood, which is indicative of endotoxicity, decreased with the introduction of prebiotic oligosaccharides into a control diet. With the lean mice, LPS dropped from around 1 to about .8; in the obese mice, LPS levels decreased from around 3, to the control baseline of 1. (Figure D) This suggests that as A. Muciniphila levels in the gut microbiome increase, the permeability of the guy decreases, thus inhibiting endotoxicity and obesity, type I diabetes and other similar conditions."
That fact that all of that makes sense to me, is kinda troubling.
Wednesday, June 18, 2014
Saturday, June 7, 2014
New blog
Since I've kind of turned a corner in life, heading back to school, I figured I would go ahead start a new blog.
Main news here is am am getting married in three weeks. Sarah and I were gunna wait until July, but some circumstances have come up and we are moving the date to the 28th of this month. It's been quite hectic, but things are happening regardless. We've got a great deal on a place. We're renting a basement for 375 a month.
This semester seems to be going better than last. I ended last semester pretty well, though. I got 91st percentile on the ACS and I got an 88 on my pre-calc final. I only ended up with a 79 in pre-calc, though, so I'm taking Algebra and trig this semester. I bombed my biology test last week, so I can still get an A-, but realistically I'll end up with a B. I have an A+ in Algebra and an B in Psych. Trig doesn't start until Monday, and it's four classes a week. I have an hour and a half between each class, which has been helpful for studying and homework, except I don't do a good job using it. I only have one class on tuesday and thursday. I'm tutoring on tuesdays and I am playing flag football as well. The football is going alright... I scored a touchdown our first game and had two sacks, then I didn't do much of anything aside from a couple of tackles until thursday. I had two sacks and two tackles for loss, and I had a lot of rushed passes. The other team didn't seem to like losing to us, and didn't seem to like that I could get in their backfield every play. The refs were pretty fed up with then complaining. I did however get away with a foul at the end. I was tired of the qb running his mouth, so I "accidentally" shoved him to the ground while reaching for his flag on a fourth-and-goal.
Overall things are alright. Wedding stress and all, but it's a going.
Main news here is am am getting married in three weeks. Sarah and I were gunna wait until July, but some circumstances have come up and we are moving the date to the 28th of this month. It's been quite hectic, but things are happening regardless. We've got a great deal on a place. We're renting a basement for 375 a month.
This semester seems to be going better than last. I ended last semester pretty well, though. I got 91st percentile on the ACS and I got an 88 on my pre-calc final. I only ended up with a 79 in pre-calc, though, so I'm taking Algebra and trig this semester. I bombed my biology test last week, so I can still get an A-, but realistically I'll end up with a B. I have an A+ in Algebra and an B in Psych. Trig doesn't start until Monday, and it's four classes a week. I have an hour and a half between each class, which has been helpful for studying and homework, except I don't do a good job using it. I only have one class on tuesday and thursday. I'm tutoring on tuesdays and I am playing flag football as well. The football is going alright... I scored a touchdown our first game and had two sacks, then I didn't do much of anything aside from a couple of tackles until thursday. I had two sacks and two tackles for loss, and I had a lot of rushed passes. The other team didn't seem to like losing to us, and didn't seem to like that I could get in their backfield every play. The refs were pretty fed up with then complaining. I did however get away with a foul at the end. I was tired of the qb running his mouth, so I "accidentally" shoved him to the ground while reaching for his flag on a fourth-and-goal.
Overall things are alright. Wedding stress and all, but it's a going.
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